Gather and prep all ingredients. Crush pepper flakes and fennel seeds using a mortar and pestle.
Pre-heat oven to 350 degrees.
In a large sauté pan, start browning the ground beef. When almost done add the onions, mushrooms, bell pepper, and seasonings. Sauté for about 5 minutes.
While sautéing meat and veggies, cook pasta to al dente according to package directions. Drain and set aside until needed.
In the saute pan or a bowl, combine the meat mixture, tomato sauce and diced tomatoes, pasta, and cheese.
Spray a 4 (to 6)-quart casserole dish with cooking spray and add pasta mixture. Top with bread crumbs and Parmesan cheese. Cover and bake for 30 minutes until bubbly.
Enjoy!